Reactions O F Extracts O F Reiter Treponeme Sera in the Single Radial Haemolysis Technique with Syphilitic and Non-syphilitic Human
نویسنده
چکیده
A single radial haemolysis (SRH) technique, using Reiter protein or Reiter lysate as the coating antigen, was investigated. Results obtained with syphilitic and presumed non-syphilitic human sera were compared with results obtained in the absorbed fluorescent treponemal antibody test (FTA-ABS), the Reiter protein complement fixation test (RPCFT), the Venereal Diseases Research Laboratory Slide test (VDRL) and the Cardiolipin Wasserman reaction (CWR). The SRH reaction, with either Reiter antigen, was more sensitive than any of the screening tests (RPCFT, VDRL and CWR) for detecting positive syphilitic antibodies. Although the SRH test used almost the same materials as the RPCFT, it was appreciably more sensitive for the detection of the group-specific antibodies in syphilitic human serum.
منابع مشابه
On the Presence in Syphilitic Serum of Antibodies to Spirochetes, Their Relation to so Called Wassermann Reagin, and Their Significance for the Serodiagnosis of Syphilis
1. In confirmation of Gaehtgens, syphilitic human sera give positive complement fixation with cultures of so called T. pallidum (Reiter strain). Syphilitic rabbit sera are equally reactive. Syphilitic human and rabbit sera agglutinate these cultures, often in high titre (Beck). 2. Normal rabbit sera react weakly with the culture to give both agglutination and complement fixation in low titre. N...
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